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7 results (View BibTeX file of all listed publications)

2009

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Fields of Experts

Roth, S., Black, M. J.

International Journal of Computer Vision (IJCV), 82(2):205-29, April 2009 (article)

Abstract
We develop a framework for learning generic, expressive image priors that capture the statistics of natural scenes and can be used for a variety of machine vision tasks. The approach provides a practical method for learning high-order Markov random field (MRF) models with potential functions that extend over large pixel neighborhoods. These clique potentials are modeled using the Product-of-Experts framework that uses non-linear functions of many linear filter responses. In contrast to previous MRF approaches all parameters, including the linear filters themselves, are learned from training data. We demonstrate the capabilities of this Field-of-Experts model with two example applications, image denoising and image inpainting, which are implemented using a simple, approximate inference scheme. While the model is trained on a generic image database and is not tuned toward a specific application, we obtain results that compete with specialized techniques.

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2009

Roth, S., Black, M. J. Fields of Experts International Journal of Computer Vision (IJCV), 82(2):205-29, April 2009 (article)

pdf pdf from publisher [BibTex]

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Left Ventricular Regional Wall Curvedness and Wall Stress in Patients with Ischemic Dilated Cardiomyopathy

Liang Zhong, Yi Su, Si Yong Yeo, Ru San Tan Dhanjoo Ghista, Ghassan Kassab

American Journal of Physiology – Heart and Circulatory Physiology, 296(3):H573-84, 2009 (article)

Abstract
Geometric remodeling of the left ventricle (LV) after myocardial infarction is associated with changes in myocardial wall stress. The objective of this study was to determine the regional curvatures and wall stress based on three-dimensional (3-D) reconstructions of the LV using MRI. Ten patients with ischemic dilated cardiomyopathy (IDCM) and 10 normal subjects underwent MRI scan. The IDCM patients also underwent delayed gadolinium-enhancement imaging to delineate the extent of myocardial infarct. Regional curvedness, local radii of curvature, and wall thickness were calculated. The percent curvedness change between end diastole and end systole was also calculated. In normal heart, a short- and long-axis two-dimensional analysis showed a 41 +/- 11% and 45 +/- 12% increase of the mean of peak systolic wall stress between basal and apical sections, respectively. However, 3-D analysis showed no significant difference in peak systolic wall stress from basal and apical sections (P = 0.298, ANOVA). LV shape differed between IDCM patients and normal subjects in several ways: LV shape was more spherical (sphericity index = 0.62 +/- 0.08 vs. 0.52 +/- 0.06, P < 0.05), curvedness at end diastole (mean for 16 segments = 0.034 +/- 0.0056 vs. 0.040 +/- 0.0071 mm(-1), P < 0.001) and end systole (mean for 16 segments = 0.037 +/- 0.0068 vs. 0.067 +/- 0.020 mm(-1), P < 0.001) was affected by infarction, and peak systolic wall stress was significantly increased at each segment in IDCM patients. The 3-D quantification of regional wall stress by cardiac MRI provides more precise evaluation of cardiac mechanics. Identification of regional curvedness and wall stresses helps delineate the mechanisms of LV remodeling in IDCM and may help guide therapeutic LV restoration.

[BibTex]

Liang Zhong, Yi Su, Si Yong Yeo, Ru San Tan Dhanjoo Ghista, Ghassan Kassab Left Ventricular Regional Wall Curvedness and Wall Stress in Patients with Ischemic Dilated Cardiomyopathy American Journal of Physiology – Heart and Circulatory Physiology, 296(3):H573-84, 2009 (article)

[BibTex]

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A Curvature-Based Approach for Left Ventricular Shape Analysis from Cardiac Magnetic Resonance Imaging

Si Yong Yeo, Liang Zhong, Yi Su, Ru San Tan, Dhanjoo Ghista

Medical & Biological Engineering & Computing, 47(3):313-322, 2009 (article)

Abstract
It is believed that left ventricular (LV) regional shape is indicative of LV regional function, and cardiac pathologies are often associated with regional alterations in ventricular shape. In this article, we present a set of procedures for evaluating regional LV surface shape from anatomically accurate models reconstructed from cardiac magnetic resonance (MR) images. LV surface curvatures are computed using local surface fitting method, which enables us to assess regional LV shape and its variation. Comparisons are made between normal and diseased hearts. It is illustrated that LV surface curvatures at different regions of the normal heart are higher than those of the diseased heart. Also, the normal heart experiences a larger change in regional curvedness during contraction than the diseased heart. It is believed that with a wide range of dataset being evaluated, this approach will provide a new and efficient way of quantifying LV regional function.

link (url) [BibTex]

Si Yong Yeo, Liang Zhong, Yi Su, Ru San Tan, Dhanjoo Ghista A Curvature-Based Approach for Left Ventricular Shape Analysis from Cardiac Magnetic Resonance Imaging Medical & Biological Engineering & Computing, 47(3):313-322, 2009 (article)

link (url) [BibTex]

2007

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Learning static Gestalt laws through dynamic experience

Ostrovsky, Y., Wulff, J., Sinha, P.

Journal of Vision, 7(9):315-315, ARVO, June 2007 (article)

Abstract
The Gestalt laws (Wertheimer 1923) are widely regarded as the rules that help us parse the world into objects. However, it is unclear as to how these laws are acquired by an infant's visual system. Classically, these “laws” have been presumed to be innate (Kellman and Spelke 1983). But, more recent work in infant development, showing the protracted time-course over which these grouping principles emerge (e.g., Johnson and Aslin 1995; Craton 1996), suggests that visual experience might play a role in their genesis. Specifically, our studies of patients with late-onset vision (Project Prakash; VSS 2006) and evidence from infant development both point to an early role of common motion cues for object grouping. Here we explore the possibility that the privileged status of motion in the developmental timeline is not happenstance, but rather serves to bootstrap the learning of static Gestalt cues. Our approach involves computational analyses of real-world motion sequences to investigate whether primitive optic flow information is correlated with static figural cues that could eventually come to serve as proxies for grouping in the form of Gestalt principles. We calculated local optic flow maps and then examined how similarity of motion across image patches co-varied with similarity of certain figural properties in static frames. Results indicate that patches with similar motion are much more likely to have similar luminance, color, and orientation as compared to patches with dissimilar motion vectors. This regularity suggests that, in principle, common motion extracted from dynamic visual experience can provide enough information to bootstrap region grouping based on luminance and color and contour continuation mechanisms in static scenes. These observations, coupled with the cited experimental studies, lend credence to the hypothesis that static Gestalt laws might be learned through a bootstrapping process based on early dynamic experience.

link (url) DOI [BibTex]

2007

Ostrovsky, Y., Wulff, J., Sinha, P. Learning static Gestalt laws through dynamic experience Journal of Vision, 7(9):315-315, ARVO, June 2007 (article)

link (url) DOI [BibTex]

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Neuromotor prosthesis development

Donoghue, J., Hochberg, L., Nurmikko, A., Black, M., Simeral, J., Friehs, G.

Medicine & Health Rhode Island, 90(1):12-15, January 2007 (article)

Abstract
Article describes a neuromotor prosthesis (NMP), in development at Brown University, that records human brain signals, decodes them, and transforms them into movement commands. An NMP is described as a system consisting of a neural interface, a decoding system, and a user interface, also called an effector; a closed-loop system would be completed by a feedback signal from the effector to the brain. The interface is based on neural spiking, a source of information-rich, rapid, complex control signals from the nervous system. The NMP described, named BrainGate, consists of a match-head sized platform with 100 thread-thin electrodes implanted just into the surface of the motor cortex where commands to move the hand emanate. Neural signals are decoded by a rack of computers that displays the resultant output as the motion of a cursor on a computer monitor. While computer cursor motion represents a form of virtual device control, this same command signal could be routed to a device to command motion of paralyzed muscles or the actions of prosthetic limbs. The researchers’ overall goal is the development of a fully implantable, wireless multi-neuron sensor for broad research, neural prosthetic, and human neurodiagnostic applications.

pdf [BibTex]

Donoghue, J., Hochberg, L., Nurmikko, A., Black, M., Simeral, J., Friehs, G. Neuromotor prosthesis development Medicine & Health Rhode Island, 90(1):12-15, January 2007 (article)

pdf [BibTex]

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On the spatial statistics of optical flow

Roth, S., Black, M. J.

International Journal of Computer Vision, 74(1):33-50, 2007 (article)

Abstract
We present an analysis of the spatial and temporal statistics of "natural" optical flow fields and a novel flow algorithm that exploits their spatial statistics. Training flow fields are constructed using range images of natural scenes and 3D camera motions recovered from hand-held and car-mounted video sequences. A detailed analysis of optical flow statistics in natural scenes is presented and machine learning methods are developed to learn a Markov random field model of optical flow. The prior probability of a flow field is formulated as a Field-of-Experts model that captures the spatial statistics in overlapping patches and is trained using contrastive divergence. This new optical flow prior is compared with previous robust priors and is incorporated into a recent, accurate algorithm for dense optical flow computation. Experiments with natural and synthetic sequences illustrate how the learned optical flow prior quantitatively improves flow accuracy and how it captures the rich spatial structure found in natural scene motion.

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Roth, S., Black, M. J. On the spatial statistics of optical flow International Journal of Computer Vision, 74(1):33-50, 2007 (article)

pdf preprint pdf from publisher [BibTex]

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Assistive technology and robotic control using MI ensemble-based neural interface systems in humans with tetraplegia

Donoghue, J. P., Nurmikko, A., Black, M. J., Hochberg, L.

Journal of Physiology, Special Issue on Brain Computer Interfaces, 579, pages: 603-611, 2007 (article)

Abstract
This review describes the rationale, early stage development, and initial human application of neural interface systems (NISs) for humans with paralysis. NISs are emerging medical devices designed to allowpersonswith paralysis to operate assistive technologies or to reanimatemuscles based upon a command signal that is obtained directly fromthe brain. Such systems require the development of sensors to detect brain signals, decoders to transformneural activity signals into a useful command, and an interface for the user.We review initial pilot trial results of an NIS that is based on an intracortical microelectrode sensor that derives control signals from the motor cortex.We review recent findings showing, first, that neurons engaged by movement intentions persist in motor cortex years after injury or disease to the motor system, and second, that signals derived from motor cortex can be used by persons with paralysis to operate a range of devices. We suggest that, with further development, this form of NIS holds promise as a useful new neurotechnology for those with limited motor function or communication.We also discuss the additional potential for neural sensors to be used in the diagnosis and management of various neurological conditions and as a new way to learn about human brain function.

pdf preprint pdf from publisher DOI [BibTex]

Donoghue, J. P., Nurmikko, A., Black, M. J., Hochberg, L. Assistive technology and robotic control using MI ensemble-based neural interface systems in humans with tetraplegia Journal of Physiology, Special Issue on Brain Computer Interfaces, 579, pages: 603-611, 2007 (article)

pdf preprint pdf from publisher DOI [BibTex]